Ryanair has said it will close its base at Glasgow International from November this year, potentially with the loss of 300 jobs.
The low-cost carrier currently has one aircraft based in the Scottish city.
Over the summer, Ryanair will offer 23 routes out of Glasgow, including to Alicante, Gran Canaria, and Malaga.
However, this will then fall to three routes from winter this year.
Ryanair made the announcement as it unveiled its schedule for winter 2018, confirming that only its services to Dublin, Wroclaw and Krakow would continue from Glasgow.
The decision means routes to Derry, Lisbon, Sofia, Riga, and Berlin will all switch to Edinburgh.
The Scottish capital will then offer a total of 45 routes, including Berlin, Derry, Gothenburg, Hamburg, Lisbon, Memmingen, Riga, Seville, Sofia, and Tallinn.
“Ryanair regrets these cuts in the weaker Glasgow market where efforts to stimulate low fare demand are severely hampered by the continuing burden of air passenger duty,” explained Ryanair chief commercial officer, David O’Brien.
The Scottish government unveiled plans to replace air passenger duty with a cheaper air departure tax in 2017.
However, the plans have yet to be implemented and require EU approval under state aid rules.